Your resilience matters. So does your HIV treatment.

SYMTUZA™ contains darunavir, which can help you keep fighting HIV with its high barrier to HIV drug resistance.


SYMTUZA™ is just one pill a day

Once-daily SYMTUZA™ is a complete treatment regimen in one pill taken for HIV-1 infection in adults who have never received HIV medicines in the past, or whose healthcare providers have determined that they meet certain requirements. It contains 800 mg darunavir/150 mg cobicistat/200 mg emtricitabine/10 mg tenofovir alafenamide fumarate.

A high barrier to drug resistance can help keep fighting HIV

Even if you only miss a few doses of your HIV treatment every once in a while, this gives the HIV a chance to change. Once this happens, you may develop HIV drug resistance against certain types of HIV medications. Some people think of this as the virus outsmarting the treatment.

This means:

  • Your current HIV medication may stop working—this could cause your viral load to go up and make your CD4+ cell count go down, weakening your immune system
  • Your future treatment options may become limited
  • HIV drug resistance can also be passed on to others

SYMTUZA™ may keep working even if 
the HIV virus has changed

Non-mutated HIV and Mutated HIV

Treatment without high barrier to HIV drug resistance

Treatment without high barrier to resistance

Treatment with high barrier to HIV drug resistance

Treatment with high barrier to resistance

SYMTUZA™ has a high barrier to HIV drug resistance, which means it may keep on working even if the virus has changed. While some medications become less effective after the virus changes, those with a high barrier to resistance bind tightly to the virus and may continue to work even after several changes occur, reducing the risk of developing drug resistance.

Consider your bone and kidney health

With or without HIV, bone and kidney health are essential for our bodies to function properly. Some HIV treatments may negatively affect your bone and kidneys; that’s why it’s important to talk to your healthcare provider about how SYMTUZA™ may have less impact on your bone and kidney health than some other HIV treatments.*

The long-term impact of changes in bone health is not known.

*The other treatments in these studies were Truvada® + PREZCOBIX®, PREZISTA®/Norvir®, Evotaz®, Reyataz®/Norvir®, or Kaletra®.

Speak up for yourself so 
your healthcare provider can help you

Healthcare providers want to help you, and they want to know the facts. They are proud of their patients, especially the ones who are willing to discuss all parts of their lives that may affect their HIV. Not only does this give them a chance to admire your strength to be open, but they will have a lot more information to help prescribe the right treatment plan for you.

But it can be hard to let healthcare providers know that you’ve missed doses of your HIV treatment or that you’re concerned if your HIV treatment is working correctly. The thing is, healthcare providers understand that nobody is perfect. When you’re open with your healthcare provider about the way you live your life, it may be easier for them to help you find treatment options that may be better suited for you.