Your resilience matters. So does your HIV treatment.

SYMTUZA® contains darunavir, which can help you keep fighting HIV with its high barrier to HIV drug resistance.



SYMTUZA® is just one pill a day

Once-daily SYMTUZA® is a complete treatment regimen in one pill taken for HIV-1 infection in adults who have never received HIV medicines in the past, or whose healthcare providers have determined that they meet certain requirements. It contains 800 mg darunavir/150 mg cobicistat/200 mg emtricitabine/10 mg tenofovir alafenamide fumarate.

A high barrier to drug resistance can help keep fighting HIV

Even if you only miss a few doses of your HIV treatment every once in a while, this gives the HIV a chance to change. Once this happens, you may develop HIV drug resistance against certain types of HIV medications. Some people think of this as the virus outsmarting the treatment.

This means:

  • Your current HIV medication may stop working—this could cause your viral load to go up and make your CD4+ cell count go down, weakening your immune system
  • Your future treatment options may become limited
  • HIV drug resistance can also be passed on to others

SYMTUZA® may keep working even if 
the HIV virus has changed

Non-mutated HIV and Mutated HIV

Treatment without high barrier to HIV drug resistance

Treatment without high barrier to resistance

Treatment with high barrier to HIV drug resistance

Treatment with high barrier to resistance

SYMTUZA® has a high barrier to HIV drug resistance, which means it may keep on working even if the virus has changed. While some medications become less effective after the virus changes, those with a high barrier to resistance bind tightly to the virus and may continue to work even after several changes occur, reducing the risk of developing drug resistance.

Consider your bone and kidney health

With or without HIV, bone and kidney health are essential for our bodies to function properly. Some HIV treatments may negatively affect your bone and kidneys; that’s why it’s important to talk to your healthcare provider about how SYMTUZA® may have less impact on your bone and kidney health than some other HIV treatments.*

The long-term impact of changes in bone health is not known.

*The other treatments in these studies were Truvada® + PREZCOBIX®, PREZISTA®/Norvir®, Evotaz®, Reyataz®/Norvir®, or Kaletra®.

Talk to your healthcare provider about your options

If you’re thinking about starting or switching HIV medications, check out the SYMTUZA® Conversation Starter. It can help you be more open and honest with yourself as you discuss treatment options with your healthcare provider, especially if you’ve forgotten doses of other medications in the past or think you might miss doses of your new treatment.